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Theophylline is an oral bronchodilator medicine which is prescribed for people with breathing problems, such as asthma and chronic obstructive pulmonary disease (COPD). It is a medicine that you take by mouth, as a tablet or capsule. Theophylline works by opening up the air passages in your lungs so that air can flow into your lungs more freely.
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Typical dosing for Theophylline. Children who weigh less than 45 kg (99 lbs) typically start with 12 to 14 mg/kg per day, but no more than 300 mg in a day. Their dose can be as high as 20 mg/kg per day, but no more than 600 mg in a day. Adults and children who weigh over 45 kg typically start with 300 to 400 mg per day.
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Theophylline is a medication used to treat asthma and chronic obstructive pulmonary disease as a second-line drug. It is a bronchodilator. This activity reviews the indications, action, and contraindications for theophylline as a potential agent in treating asthma and chronic obstructive pulmonary disease. This activity will highlight the mechanism of action, adverse event profile.
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Theophylline extended-release tablets in Japan. Theophylline, also known as 1,3-dimethylxanthine, is a drug that inhibits phosphodiesterase and blocks adenosine receptors. It is used to treat chronic obstructive pulmonary disease (COPD) and asthma. Its pharmacology is similar to other methylxanthine drugs (e.g., theobromine and caffeine). Trace amounts of theophylline are naturally present in.
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Theophylline | C7H8N4O2 | CID 2153 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety.
THEOPHYLLINE ORAL SOLUTION PAI
Generic Name Theophylline DrugBank Accession Number DB00277 Background. A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities.
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Bookshelf ID: NBK532962 PMID: 30422557. Around the world, theophylline (1,3-dimethylxanthine) is primarily used as a bronchodilator for patients with asthma and chronic obstructive pulmonary disease (COPD). However, in the United States, asthma and COPD are mainly treated with other agents, and theophylline is largely used to treat bradycardia.
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Some of the more common side effects that can occur with use of theophylline include: headache. trouble sleeping. If these effects are mild, they may go away within a few days or a couple of weeks.
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The theophylline is coated onto a sugar/starch pellet by means of an adhesive such as cellulose acetate phthalate which will not dissolve in stomach juices. [0009] U.S. Patent No. 4,261,970 describes a sustained release theophylline granule containing a metal salt of a fatty acid and ethyl cellulose.
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Dose: 0.2 mg/kg/h IV; Start: load 5 mg/kg/dose IV x1 if no theophylline w/in 24h; Info: not recommended per NIH guidelines; adjust dose based on serum levels; reduced clearance risk factors include hepatic impairment, CHF, fever, sepsis w/ multi-organ failure, shock, and hypothyroidism.
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Side Effects. Nausea / vomiting, stomach / abdominal pain, headache, trouble sleeping, diarrhea, irritability, restlessness, nervousness, shaking, or increased urination may occur. If any of these.
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Theophylline belongs to a group of medicines known as bronchodilators. Bronchodilators are medicines that relax the muscles in the bronchial tubes (air passages) of the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes. This medicine is available only with.
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What are the generic sources for theophylline and what is the scope of patent protection? Theophylline is the generic ingredient in fifty-two branded drugs marketed by Fleming Pharms, Forest Labs, Sanofi Aventis Us, Graham Dm, Auxilium Pharms Llc, Schering, Whitby, Schwarz Pharma, Ortho Mcneil Pharm, Cent Pharms, Hospira, Inwood Labs, Sandoz.
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Theophylline may cause serious side effects. Call your doctor at once if you have: severe or continued vomiting; ongoing headache, trouble sleeping; rapid heartbeats; a seizure; new signs of illness (especially fever); low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination.
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This includes your doctors, nurses, pharmacists, and dentists. This drug may affect certain lab tests. Tell all of your health care providers and lab workers that you take this drug. Wear disease medical alert ID (identification). Have blood work checked as you have been told by the doctor. Talk with the doctor.
Theophylline Uses, Interactions, Mechanism of Action DrugBank Online
The invention discloses a high-yield synthesis method for theophylline. The high-yield synthesis method for theophylline comprises the following steps: adding dimethyl sulphate, 6-aminouracil, a sodium hydroxide solution and water in a reaction container, stirring in an ice-salt bath, filtering, washing and drying to obtain 6-amino-1,3-dimethyluracil; adding 6-amino-1,3-dimethyluracil, acetic.