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8-chloro-1,3-dimethyl-7H-purine-2,6-dione 2- (diphenylmethyl)oxy-N,N-dimethylethanamine is a diarylmethane. Dimehydrinate was first described in the literature in 1949, and patented in 1950. Early research into dimenhydrinate focused on its role as an antihistamine for urticaria; the treatment of motion sickness was an accidental discovery.
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Dimenhydrinate (dimenhidrinat) bermanfaat untuk mencegah atau mengobati mual, muntah, atau pusing berputar (vertigo) akibat mabuk perjalanan. Obat ini dapat dibeli bebas, tetapi penggunaannya memerlukan perhatian khusus. Dimenhydrinate merupakan obat golongan antihistamin generasi pertama. Obat ini mencegah mual dan muntah dengan cara menghambat rangsangan yang berlebihan pada sistem.
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Find medical information for dimenhydrinate on epocrates online, including its dosing, contraindications, drug interactions, and pill pictures.
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Manfaat Dimenhydrinate. Beberapa manfaat obat ini adalah mencegah dan mengobati mual, muntah, dan pusing, terutama yang terjadi akibat mabuk perjalanan. Obat ini termasuk dalam golongan antihistamin. Ia bekerja dengan mencegah masalah dengan menjaga keseimbangan tubuh. Terkadang, obat ini juga bisa kamu manfaatkan untuk mengobati penyakit meniere.
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severe drowsiness; wheezing, trouble breathing, severe or worsening cough; blurred vision, eye pain or redness, seeing halos around lights; or. painful or difficult urination. Less serious side effects may be more likely, or you may have none at all. This is not a complete list of side effects and others may occur.
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little or no urination; confusion, mood changes; tremors, restlessness; a seizure (convulsions); or. fast or irregular heartbeats. Side effects such as dry mouth, constipation, and confusion may.
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Introduction. Oral drug delivery systems have wide admission up to 50-60% of total solid dosage forms. Solid dosage forms are favorite because of simplicity of administration, exact dosage, self-medication, pain avoidance and significantly the patient compliance [].Low disintegration time of tablet results in fast dissolution and speedy absorption which prepare rapid onset of clinical outcome [].
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This includes your child's doctors, nurses, pharmacists, and dentists. Do not give your child more of this drug than what the doctor told you to give. Giving more of this drug than you are told may raise the chance of severe side effects. Do not have your child use longer than you have been told by your child's doctor.
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Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate, is indicated to prevent nausea, vomiting, and dizziness caused by motion sickness. 9, 10, 11 Dimenhydrinate is a combination of Diphenhydramine and 8-chlorotheophylline in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8.
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Methods. Adult male and female outpatients were subjected to a 4-week treatment with the fixed combination of cinnarizine 20 mg and dimenhydrinate 40 mg, cinnarizine (20 mg, 50 mg), dimenhydrinate (40 mg, 100 mg), betahistine dimesylate (12 mg), betahistine dihydrochloride (16 mg) and placebo, respectively.
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Common Adverse Effects. Drowsiness, headache, blurred vision, tinnitus, dryness of the mouth and respiratory passages, incoordination, palpitation, dizziness, hypotension. Paradoxical CNS stimulation in pediatric patients and occasionally in adults. With IM injection: Pain at the injection site.
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Dimenhydrinate comes as a tablet and chewable tablet to take by mouth with or without food. To prevent motion sickness, the first dose should be taken 30 minutes to 1 hour before you travel or begin motion activity. Adults and children older than age 12 may usually take dimenhydrinate every 4 to 6 hours as needed to prevent or treat motion.
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Oral products: Fixed dose: Administer initial dose 30 to 60 minutes before travel/activity. Children ≥2 to <6 years: Oral: 12.5 to 25 mg every 6 to 8 hours; maximum daily dose: 75 mg/24 hours. Children ≥6 years to <12 years: Oral: 25 to 50 mg every 6 to 8 hours; maximum daily dose: 150 mg/24 hours.
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Side Effects. Drowsiness, constipation, blurred vision, or dry mouth /nose/throat may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To relieve dry.
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Pregnancy. Pregnancy Category B. Reproduction studies have been performed in rats at doses up to 20 times the human dose, and in rabbits at doses up to 25 times the human dose (on a mg/kg basis), and have revealed no evidence of impaired fertility or harm to the fetus due to dimenhydrinate.
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Dimenhydrinate is a medication used to prevent and treat nausea, vomiting, and vertigo associated with motion sickness. Dimenhydrinate has a potential for abuse because of its hallucinogenic and euphoric effects. Common side effects of dimenhydrinate include dizziness, drowsiness, sedation, headache, insomnia, lethargy, excitement, nervousness, restlessness, euphoria, delirium, irritability.